With Fabinho, Alex Oxlade-Chamberlain, Xherdan Shaqiri, Joel Matip and Dejan Lovren also injured, Klopp is short of options, with players at risk of injury following an intense period where they also travelled to Qatar to win the Club World Cup.
It was current Everton manager Carlo Ancelotti who in charges of Los Blancos when Rodriguez was signed from AS Monaco back in 2014, while the pair also worked together at Bayern Munich. I will decide some things myself and some things the medical department will tell me.
'We are going to play against the best team in this moment, they are world champions so congratulations to them, but this is a fantastic challenge for us'.
I think it's pretty much the same situation, I'm not 100 per cent sure. He has started already really well and this is an opportunity for Everton to win at Anfield for the first time in a few years.
"We will have fresh legs and what we need is support".
"I don't know exactly what he has - it was the groin - but I can say already he will not be involved against Everton", Klopp said.
"That's what the little talk we had, we really signed Takumi Minamino from Salzburg, the guy who played against us like insane".
Jurgen Klopp remains unsure about whether or not Takumi Minamino will make his Liverpool debut this weekend.
"That makes it 12 senior players we have, plus the kids. We should not take things like this for granted", he said in further comments published by BBC Sport.
"That's really nice, I think he felt that".
"Everybody who has played football has had this kind of injury, it's not nice".
Liverpool were grateful, therefore, that an early goal from Mohamed Salah and one from Sadio Mane midway through the second half meant they did not have to over-exert themselves against Sheffield United. I can't ask them to run 11 just to save energy for the next game.
"I thought Dean Henderson (the goalkeeper) was the difference between it being three, four or five".
New boss Carlo Ancelotti wants to strengthen his side in order to boost their chances of finishing in the top-seven, and he has specifically requested the club to seal a move for the defender.